Adrenal failure in the critically ill

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Adrenal failure in the critically ill.

Three critically ill patients suffered multiple organ failure secondary to sepsis. Despite adequate supportive therapy and appropriate antibiotic cover, they failed to improve and required inappropriate inotrope support. They had not been treated with steroids or other drugs known to suppress adrenal function. Adrenal insufficiency was suspected. A random cortisol concentration and a short syna...

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Diagnosis of adrenal failure in critically ill patients.

In the last two decades there was important evolution on the knowledge of the function of the hypothalamic-pituitary-adrenal axis. In the last decade, the expression "relative adrenal insufficiency" (RAI) was created, and more recently "critical illness-related corticosteroid insufficiency" (CIRCI) was used to designate those patients in which cortisol production was not sufficiently increased ...

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Diagnosis of adrenal failure in critically ill patients Diagnóstico de insuficiência adrenal em pacientes críticos

In the last two decades there was important evolution on the knowledge of the function of the hypothalamic-pituitary-adrenal axis. In the last decade, the expression “relative adrenal insufficiency” (RAI) was created, and more recently “critical illness-related corticosteroid insufficiency” (CIRCI) was used to designate those patients in which cortisol production was not sufficiently increased ...

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Adrenal insufficiency in critically ill patients.

Adrenal insufficiency means hypo function of the adrenal cortex, usually resulting in low glucocorticoid level and it may be associated with low mineralocorticoid, rarely low adrenal androgen level. It can be categorized into two types: primary and secondary. Primary adrenal insufficiency or Addison's disease is associated with low cortisol and high ACTH level. Secondary/tertiary adrenal insuff...

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Acute renal failure in the critically ill.

PURPOSE OF REVIEW Acute renal failure occurs frequently in hospitalized patients and is associated with significant morbidity and mortality. An effort to better understand the epidemiology and pathophysiology of this disease will hopefully lead to improvement in patient outcomes. Considerable effort has been expended to develop techniques to prevent acute renal failure or to facilitate its reso...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1998

ISSN: 0007-0912

DOI: 10.1093/bja/81.3.468